diff --git a/debian/changelog b/debian/changelog
index fec4827a..bf2595da 100644
--- a/debian/changelog
+++ b/debian/changelog
@@ -1,6 +1,15 @@
 byobu (5.58) unreleased; urgency=low
 
-  * UNRELEASED
+  * usr/share/byobu/keybindings/f-keys.tmux,
+    usr/share/byobu/keybindings/f-keys.tmux.disable,
+    usr/share/byobu/keybindings/Makefile.am,
+    usr/share/byobu/keybindings/mouse.tmux.disable,
+    usr/share/byobu/keybindings/mouse.tmux.enable,
+    usr/share/doc/byobu/help.tmux.txt:
+    - add support for a new keybinding, Alt-F12, to toggle on/off
+      tmux mouse support
+    - display a message when toggling either on or off mouse or
+      F-keys support
 
  -- Dustin Kirkland <kirkland@ubuntu.com>  Tue, 03 Sep 2013 14:40:09 -0500
 
diff --git a/usr/share/byobu/keybindings/Makefile.am b/usr/share/byobu/keybindings/Makefile.am
index fcd65eee..3defbb66 100644
--- a/usr/share/byobu/keybindings/Makefile.am
+++ b/usr/share/byobu/keybindings/Makefile.am
@@ -1,2 +1,2 @@
 keybindingsdir = $(datadir)/@PACKAGE@/keybindings
-keybindings_DATA = common f-keys f-keys.screen f-keys.screen.disable f-keys.tmux f-keys.tmux.disable none tmux-screen-keys.conf
+keybindings_DATA = common f-keys f-keys.screen f-keys.screen.disable f-keys.tmux f-keys.tmux.disable mouse.tmux.disable mouse.tmux.enable none tmux-screen-keys.conf
diff --git a/usr/share/byobu/keybindings/f-keys.tmux b/usr/share/byobu/keybindings/f-keys.tmux
index 516f9655..ab17b47d 100644
--- a/usr/share/byobu/keybindings/f-keys.tmux
+++ b/usr/share/byobu/keybindings/f-keys.tmux
@@ -72,8 +72,9 @@ bind-key -n F9 new-window -k -n config byobu-config
 bind-key -n M-F11 break-pane
 bind-key -n C-F11 join-pane -h -s :. -t :-1
 bind-key -n S-F11 join-pane -v -s :. -t :-1
-bind-key -n S-F12 source $BYOBU_PREFIX/share/byobu/keybindings/f-keys.tmux.disable
+bind-key -n S-F12 source $BYOBU_PREFIX/share/byobu/keybindings/f-keys.tmux.disable \; display-message "Byobu F-keys: DISABLED"
 bind-key -n C-S-F12 new-window $BYOBU_PREFIX/lib/byobu/include/mondrian
+bind-key -n M-F12 source $BYOBU_PREFIX/share/byobu/keybindings/mouse.tmux.enable
 bind-key -n M-IC paste-buffer
 
 bind-key -n C-a new-window -n "ctrl-a" "byobu-ctrl-a"
diff --git a/usr/share/byobu/keybindings/f-keys.tmux.disable b/usr/share/byobu/keybindings/f-keys.tmux.disable
index 0d2e5713..ab5e180a 100644
--- a/usr/share/byobu/keybindings/f-keys.tmux.disable
+++ b/usr/share/byobu/keybindings/f-keys.tmux.disable
@@ -72,7 +72,8 @@ unbind-key -n F9
 unbind-key -n M-F11
 unbind-key -n C-F11
 unbind-key -n S-F11
-bind-key -n S-F12 source $BYOBU_PREFIX/share/byobu/keybindings/f-keys.tmux
+bind-key -n S-F12 source $BYOBU_PREFIX/share/byobu/keybindings/f-keys.tmux \; display-message "Byobu F-keys: ENABLED"
+unbind-key -n M-F12
 unbind-key -n C-S-F12
 unbind-key -n M-IC
 unbind-key -n C-a
diff --git a/usr/share/byobu/keybindings/mouse.tmux.disable b/usr/share/byobu/keybindings/mouse.tmux.disable
new file mode 100644
index 00000000..01a506c4
--- /dev/null
+++ b/usr/share/byobu/keybindings/mouse.tmux.disable
@@ -0,0 +1,6 @@
+set -g mouse-resize-pane off
+set -g mouse-select-pane off
+set -g mouse-select-window off
+set -g mode-mouse off
+set -g mouse-utf8 off
+bind-key -n M-F12 source $BYOBU_PREFIX/share/byobu/keybindings/mouse.tmux.enable \; display-message "Mouse: OFF"
diff --git a/usr/share/byobu/keybindings/mouse.tmux.enable b/usr/share/byobu/keybindings/mouse.tmux.enable
new file mode 100644
index 00000000..6658df8b
--- /dev/null
+++ b/usr/share/byobu/keybindings/mouse.tmux.enable
@@ -0,0 +1,6 @@
+set -g mouse-resize-pane on
+set -g mouse-select-pane on
+set -g mouse-select-window on
+set -g mode-mouse on
+set -g mouse-utf8 off
+bind-key -n M-F12 source $BYOBU_PREFIX/share/byobu/keybindings/mouse.tmux.disable \; display-message "Mouse: ON"
diff --git a/usr/share/doc/byobu/help.tmux.txt b/usr/share/doc/byobu/help.tmux.txt
index 90996698..8ec2f39c 100644
--- a/usr/share/doc/byobu/help.tmux.txt
+++ b/usr/share/doc/byobu/help.tmux.txt
@@ -38,4 +38,5 @@ and some convenient keybindings:
     Ctrl-F11                     Join window into a vertical split
   F12                            Escape sequence
     Shift-F12                    Toggle on/off Byobu's keybindings
+    Alt-F12                      Toggle on/off Byobu's mouse support
     Ctrl-Shift-F12               Mondrian squares